As a Noun:
1. The feeling of great sadness and disappointment. English = depression, despondency, dejection, gloom.
2.
As a Verb or Adjective:
1. To feel great sadness and disappointment. English = (be) depressed, (be) dejected, (be) despondent, (be) downcast, (be) sad, (be) unhappy.
2. To make someone feel great sadness and disappointment. English = depress, sadden.