As a Noun:
1. An event or situation which you have to deal with, especially one that involves problems. English = matter, problem.
2. Damage or weakness of the body, especially the sense organs, which means that a part of your body does not work properly and seriously affects your life. English = impairment.
3. An action or opinion that is wrong, or that is not what you intended to do. English = mistake, error.
As a Verb or Adjective:
1. Of an event of situation, to involve problems.
2. To have damage or weakness in a part of the body, especially the sense organs, which means that this part of the body does not work properly. English = (be) impaired.
3. To do or think something that is wrong, or that is not what you intended to do or think. English = make a mistake, (be) mistaken.