As a Noun:
1. A person who is in charge of a particular government department. English = minister.
2. Someone who occupies a very senior and important position in an organisation or business, particularly a leadership role. English = chief executive, CEO, president.
3. The person in charge of a school or college. English = principal.
4. The person who is the head teacher at a school. English = (male) headmaster, (female) headmistress.
5. An officer in charge of a military operation or organisation. English = commander.